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Tramadol,at an average dosage of 210 mg/day,was significantly(p<0.001)more effective than placebo for treating the pain of diabetic neuropathy. Patients in the tramadol group scored significantly better in physical(p= 0.02)and social functioning(p=0.04)ratings than patients in the placebo group.No statistically significant treatment effects on sleep were identified.The most frequently occurring adverse events with tramadol were nausea,constipation,headache,and somnolence.The results of this placebo- controlled trial showed that tramadol was effective and safe in treating the pain of diabetic neuropathy. |
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diabetes mellitus
dyslexia
neuropathy
neuropathy,diabetic
neuropathy,painful
neuropathy,peripheral,treatment
pain,neuropathic
tramadol
treatment of neurologic disorder
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